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The study found that overexpression of WT BAP1 in UMRC6 cells hindered the cellular uptake of cystine, resulting in reduced GSH levels and increased erastin-induced lipid peroxidation [50]

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Cell 149:10601072 Garcia-Romo GS, Caielli S, Vega B, Connolly J, Allantaz F, Xu Z, Punaro M, Baisch J, Guiducci C, Coffman RL et al (2011) Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus

[DOI] [PMC free article] [PubMed] [Google Scholar] 144.Li Y, Hook JS, Ding Q, Xiao X, Chung SS, Mettlen M, et al

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The problem: the gastrointestinal tract breaks down most of the glutathione from food before it reaches the bloodstream