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In addition, changes in the relative proportion of COPD GOLD stages over the study period were also evaluated

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Multivariable adjusted results showed significantly elevated all-cause mortality for daily users (hazard ratio, HR = 1.22), in addition to increases in smoking-related cancers, lung cancer and chronic obstructive pulmonary disease

It requires a higher heat to burn, so it can irritate the lungs and throat upon exposure

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When smoked, the nicotine will concentrate in the end that goes into the mouth