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For example, it was recently found that that replacement of growth hormone could improve cerebral metabolism, knowledge, memory, and behavior in mild cognitive impairement (70), and that replacement of a natural signaling peptide called Gonadotropin-Releasing Hormone (GnRH) could significantly improve learning and cognition in Down's syndrome patients (71)

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Cells with increased mitochondrial activity were more resistant to 5FU treatment in the acute setting (72 h), as shown in a dose-dependent manner (Fig