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Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

J Biol Chem 279: 5534155347 JoSH,SonMK,KohHJ,LeeSM,SongIH,KimYO,LeeYS,JeongKS,KimWB,ParkJW,SongBJ,HuhTL (2001) Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP+dependent isocitrate dehydrogenase

By integrating findings from animal models, clinical imaging, and molecular biology, this work elucidates how dysfunctions in GABAergic interneurons (e.g., PV+, SST+, VIP+), GABA signaling pathways, and associated genes collectively disrupt the E/I balance in the brain, leading to core ASD symptoms such as social communication deficits, repetitive behaviors, and sensory abnormalities