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Liu, Wenchao

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GLUT4 is then translocated to the plasma membrane, where it imports glucose into the cell (325)

The key findings relevant to this question: No clinically relevant drug-metabolizing enzyme-mediated interactions have been reported for GLP-1 agonists Some transporters (OATP1B1/3, OAT3) showed inhibition with GLP-1 agonist treatment in vitro Significant changes in oral contraceptive and levothyroxine absorption were documented with tirzepatide and oral semaglutide GLP-1 agonists delay gastric emptying, which can alter absorption of co-administered oral medications Critically, no published study has examined the drug-drug interaction profile of two injectable GLP-1 agonists administered concurrently

doi: 10.1186/s12906-024-04492-4, 91

Surprisingly, its actually the thawing process that can cause a pipe to burst