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Available from: Chatterjee A, Das S, Barman S, Barman S

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International Journal of Womens Dermatology 2018

191 SkillbckT.DelsingL.SynnergrenJ.MattssonN.JanelidzeS.NggaK.et al (2017)

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It is considered that placing three consecutive 2-F moieties, instead of larger groups, at the middle of the sense strand aims to facilitate the cleavage and removal of the sense strand in RISC, as release of the sense strand is the prerequisite of RISC activation