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47,48 Also, greater percentage of total GSH exists in the oxidized form in patients with ARDS than in healthy subjects, possibly indicating increased oxidant stress in the lower respiratory tract of ARDS patients

Current Opinion in Pharmacology, 19, 50-55

doi: 10.3920/BM2020.0191 33 OhY

Gemcitabine, an antimetabolite that disrupts DNA replication and is commonly used in treating pancreatic cancers, causes ROS accumulation and stimulates ferroptosis (162)

what changes between routes is not the cellular biology but whether, and in what concentration, the intact complex ever arrives at that cell in a living human

Another confounding feature, especially in transcriptomic analysis of tumors, is that IDO1 expression is increased in M1 macrophages [156], probably as a means to fine-tune the tissue-destructive effect of these cells