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Severe cases usually declare themselves within the first 12 h of symptom onset

Continuous inhalation of injurious agents directs the initiation of prolonged oxidative stress in the lungs, which results in chronic inflammation characterized by a pronounced release of reactive nitrogen and oxygen species

doi: 10.3892/mmr.2021.12313 278 RogackaDAudzeyenkaIRychowskiMRachubikPSzrejderMAngielskiSet al

10.1212/wnl.29.9_part_1.1253 125 LiD.WilkinsK.McCollumA

Other serological tests for viral load include quantification of HBeAg, a marker for high-infectivity HBV, as well as the detection of antibodies to HBV antigens (anti-HBs, anti-HBe, and anti-HBc, an antibody to the HBV core antigen), which can indicate a prior or chronic infection (WHO 2009