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This work was supported by the Francis Crick Institute, which receives its core funding from Cancer Research UK, the UK Medical Research Council, and the Wellcome Trust (CC2041)

Sustaining the engine: mitochondrial quality control and transport networks As the central engine of cellular bioenergetics and intermediary metabolism, mitochondrial functional integrity is critical for sustaining high metabolic flux, anabolic potential, and therapeutic responsiveness in CRC [18]

Reliance on Caffeine, Sugar, or Nicotine One final sign that you may be sleep-deprived is to take inventory of your daily consumption of caffeine or nicotine