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1 Introduction The intestinal wall is a complex system consisting of four layers: mucosa, submucosa, muscularis, and serosa

Under these conditions, citrulline, a byproduct of nitric oxide synthesis, can recover arginine via the arginine-citrulline pathway

This review concludes that these four plant-active ingredients and herbal compound components promote tendon-bone healing through various mechanisms

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Key Physical & Chemical Parameters The API manufacturing process hinges on controlling physical and chemical properties like bulk density, solubility, and particle size distribution

10.1186/s12951-025-03775-3 Summary Keywords antioxidants, nanodelivery systems, nanomaterials, ROS, skin disease Citation Yan Q, Zheng Y, Chen L, Ma H, Ding C, Pang X, Xia T, Wei J, Zhang Y and Xu G (2026) Reactive oxygen species in skin diseases: pathogenic mechanisms and nanomaterial-based therapeutic strategies