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mitis to hydrolyze glycan in the mucus, releasing sialic acid, a potential additional nutrient source, although meningococci were unable to grow in the presence of sialic acid as the sole carbon source, and the addition of sialic acid to the mucus of Calu3 cells was not sufficient to enhance meningococcal growth ( In particular, the study by Audry and colleagues ( N

These alterations jointly promote the buildup of metabolites and endotoxins, which in turn heighten intestinal permeability and encourage bacterial translocation [45, 46]