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Several bioactive compounds modulate cytochrome P450 enzymes, particularly CYP3A4, CYP2D6, and CYP2C9, which are essential for the metabolism of chemotherapeutic agents and endocrine therapies

This was a significant finding in that PEGylation is routinely used to increase the solubility and efficacy of drugs, especially anticancer drugs [8,9,11]

Gridelli C, Ardizzoni A, Ciardiello F, Hanna N, Heymach JV , Perrone F, Rosell R, Shepherd FA, Thatcher N, Vansteenkiste J, De Petris L, Di Maio M, De Marinis F

[7] Amino acids are formally named by the IUPAC-IUBMB Joint Commission on Biochemical Nomenclature in terms of the fictitious "neutral" structure shown in the illustration

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