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However, BDNF is suggested to show anti-epileptic effects in other studies (Cifelli et al

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Its believed to play

Excess extracellular glutamate triggers mechanisms involving astrocyte-mediated inflammation, including the release of Ca 2+ -dependent glutamate from astrocytes, the appearance of excitotoxicity, the formation of reactive oxygen species (ROS), and cell damage

At the extreme end of this situation, where there is a genetic deficit in carnitine biosynthesis, some nasty stuff happens without carnitine supplementation [1]: Liver damage and dysfunction Brain damage Muscle weakness Lethargy Exercise intolerance Yet, there can also be situations of mild deficiency where these overt signs arent present

Currently running 8-week cycles with 4-week breaks