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The study, led by Dr Chiara Herzog and published in Cancer Research , analysed the epigenetic effects of tobacco and e-cigarettes on DNA methylation on cells that are directly exposed to tobacco, such as the cells lining the cheek, and those that are not directly exposed, including blood and cervical cells

More details can be found on the NHS website

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ASH found 2.8% of 11 to 17-year-olds said they smoked cigarettes and vaped

Smokeless tobacco contains ingredients such as nicotine, areca nut/betel nut (BN), heavy metals, and various other nephrotoxic agents that are absorbed directly from the oral mucous membrane and can impair renal function and accelerate the progress of renal diseases

However, some states and cities are implementing stricter regulations, like flavor bans