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In allergic and inflammatory diseases, mast cells play a pivotal role by releasing histamine, leukotrienes, prostaglandins and various cytokines, which interact synergistically to exacerbate allergic and inflammatory symptoms (52)

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Cadmium chloride exposure specifically inhibits DNMT3A/3B activity by 70%, impairing de novo methylation processes and contributing to germline instability (89)

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Notably, our results showed MgSO effectively inhibites the rise in MAO-A activity associated with nicotine withdrawal