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WARNING: Smoking causes age-related macular degeneration, which can lead to blindness (macular degeneration)

However, people with the disease may experience one or more of the following symptoms: Abdominal pain Rectal bleeding Changes in bowel habits (usually diarrhea, but occasionally constipation) Weight loss Fever Left untreated, Crohns or medications used to treat it may lead to additional symptoms within and outside of the GI tract, such as: Bowel obstruction (blockage) Dysplasia (precancerous changes to skin, colon, and other organs) Fistulas (abnormal connections) between the bowels and other organs Fissures (tears in the anus lining) Strictures (narrowing of the intestines) Abscess (collection of pus) Skin rashes and bumps Malnutrition (due to poor nutrient absorption and vitamin deficiency) Liver complications Even when managed, Crohns can cause flare-ups or worsening symptoms throughout an individuals lifetimes

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