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10.3748/wjg.v23.i33.6016 16 FitzpatrickL

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Interestingly, reactivation of AKT/mTOR signaling by using small molecule PI3K antagonists activates the transport of energy-active mitochondria to the cortical cytoskeleton of cancer cells, therefore heightening tumor cell invasion (202)

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Although the precise location of the yawning motor center has not been identified, it is suggested to reside within the brainstem spanning from the midbrain to the medulla oblongata (Krestel et al., 2018)