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found that when cells are exposed to an environment of low sugar and other nutrient deficiencies, acetyl-CoA synthase ACSS2 will translocate to the nucleus and catalyze the production of acetyl-CoA from acetic acid, thereby mediating the acetylation of histone H3

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doi:10.1016/B978-0-12-420117-0.00003-7 [PubMed] 32

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