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Since higher values of E HOMO and lower values of E LUMO are responsible for the increased reactivity of molecules

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The enhanced efficacy of NP formulations in reducing these cytokines compared to conventional forms suggests improved cellular absorption and targeted distribution to inflamed regions

Despite their notable absence in CM, alterations in the SF3B1 gene are not unique to MM - similar mutations have also been detected in uveal melanoma, breast cancer, myelodysplastic syndromes, and chronic lymphocytic leukemia, including mutation hotspots such as codon 700, 622, 625, 662, and 666 (99, 113)

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