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Akibatnya, penderitanya dapat mengalami gejala berupa penyakit kuning, varises berdarah, ensefalopati hati, dan asites (penumpukan cairan di perut)

Microbial metabolites like SCFA and Trp derivatives can activate AhR and its target genes, including IL-6, IL-22, prostaglandin G/H synthase 2 (PTGS2), vascular endothelial growth factor A (VEGFA), and cytochrome P450 1 A1 (CYP1 A1) in the intestine or liver

Refractory cancers, such as pancreatic cancer, triple-negative breast cancer, and glioblastoma, as well as drug-resistant tumours, frequently demonstrate a high resistance to ferroptosis

Intensive Care Med 38(11):18001809

Such Gln27 mutations, along with Arg16 mutations in adults, can result in an unfavourable cardiovascular profile (7981)

2017;13(1):91-98.[DOI] 85