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For instance, the transcripts of polyoma simian virus 40 (SV40) and adenovirus, DNA viruses that replicate in the nucleus, were shown to be extensively modified 65,66

The hippocampus is not the only brain region affected by intestinal IRI-mediated neuroinflammation

Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway

In a healthy system, intracellular glutathione immediately neutralizes these free radicals, protecting the delicate mitochondrial membranes from lipid peroxidation and structural damage

The GSH:GSSG ratio compares reduced glutathione (GSH) to its oxidized disulfide form (GSSG)

To further determine the role of GSH in GLAST KO mice, it would be interesting to test whether GSH ethyl ester, which restores mitochondrial GSH in vivo 69 , can rescue RGC degeneration in GLAST KO mice